Food packaging must fulfil strict legal requirements to guarantee the safety of foods and, in turn, consumers´ health and wellbeing. This includes provisions governing the transfer (migration) of substances from the packaging into the food. As screen printing inks become part of the food packaging, the possible migration of substances from the ink film into to the food must be considered before the conformity of a food packaging can be issued. This results in various requirements for the used screen printing ink, like specific selection and purity criteria of the used raw materials as well as tailored production conditions in order to avoid process-related impurities. But also the printing conditions (effective drying and curing), the material of the food packaging (barrier properties) and other parameters like type of food and storage conditions are relevant for a safe and compliant printed food packaging.